USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q15172 USC-OGP 2-DE database:  Q15172 Q15172 General information about the entry View entry in simple text format Entry name 2A5A_HUMAN Primary accession number Q15172 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; AltName: Full=PP2A B subunit isoform B'-alpha; AltName: Full=PP2A B subunit isoform B56-alpha; AltName: Full=PP2A B subunit isoform PR61-alpha; Short=PR61alpha; AltName: Full=PP2A B subunit isoform R5-alpha;. Gene name Name=PPP2R5A Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0040: pI=5.00; Mw=61375 Cross-references UniProtKB/Swiss-Prot Q15172; 2A5A_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name 2A5A_HUMAN Primary accession number Q15172 Secondary accession number(s) B2R6D2 B7Z7L2 D3DT99 Q2NL72 Q5VVB2 Q8TBI9 Sequence was last modified on  November 1, 1996 (version 1) Annotations were last modified on  March 15, 2017 (version 160) Name and origin of the protein Description RecName: Full=Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; AltName: Full=PP2A B subunit isoform B'-alpha; AltName: Full=PP2A B subunit isoform B56-alpha; AltName: Full=PP2A B subunit isoform PR61-alpha; Short=PR61alpha; AltName: Full=PP2A B subunit isoform R5-alpha; Gene name Name=PPP2R5A Encoded on Name=PPP2R5A Keywords Acetylation; Alternative splicing; Centromere; Chromosome; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleus; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL L42373; AAC37601.1; -; mRNA EMBL AK302202; BAH13648.1; -; mRNA EMBL AK312530; BAG35429.1; -; mRNA EMBL AL451060; CAH71821.1; -; Genomic_DNA EMBL AL360091; CAH71821.1; JOINED; Genomic_DNA EMBL AL360091; CAH73229.1; -; Genomic_DNA EMBL AL451060; CAH73229.1; JOINED; Genomic_DNA EMBL CH471100; EAW93392.1; -; Genomic_DNA EMBL CH471100; EAW93393.1; -; Genomic_DNA EMBL BC022474; AAH22474.1; -; mRNA EMBL BC110883; AAI10884.1; -; mRNA CCDS CCDS1503.1; -. [Q15172-1]; . CCDS CCDS55686.1; -. [Q15172-2]; . PIR I55449; I55449; . RefSeq NP_001186685.1; NM_001199756.1. [Q15172-2]; . RefSeq NP_006234.1; NM_006243.3. [Q15172-1]; . UniGene Hs.744012; -; . ProteinModelPortal Q15172; -; . SMR Q15172; -; . BioGrid 111517; 32; . DIP DIP-459N; -; . IntAct Q15172; 27; . MINT MINT-88251; -; . STRING 9606.ENSP00000261461; -; . BindingDB Q15172; -; . ChEMBL CHEMBL4763; -; . iPTMnet Q15172; -; . PhosphoSitePlus Q15172; -; . BioMuta PPP2R5A; -; . DMDM 7387496; -; . OGP Q15172; -; . EPD Q15172; -; . MaxQB Q15172; -; . PaxDb Q15172; -; . PeptideAtlas Q15172; -; . PRIDE Q15172; -; . DNASU 5525; -; . Ensembl ENST00000261461; ENSP00000261461; ENSG00000066027. [Q15172-1]; . Ensembl ENST00000537030; ENSP00000442866; ENSG00000066027. [Q15172-2]; . GeneID 5525; -; . KEGG hsa:5525; -; . UCSC uc001hjb.3; human. [Q15172-1]; . CTD 5525; -; . DisGeNET 5525; -; . GeneCards PPP2R5A; -; . HGNC HGNC:9309; PPP2R5A; . HPA HPA059288; -; . MIM 601643; gene; . neXtProt NX_Q15172; -; . OpenTargets ENSG00000066027; -; . PharmGKB PA33672; -; . eggNOG KOG2085; Eukaryota; . eggNOG ENOG410XQJW; LUCA; . GeneTree ENSGT00550000074525; -; . HOGENOM HOG000067326; -; . HOVERGEN HBG000009; -; . InParanoid Q15172; -; . KO K11584; -; . OMA KLQNCCF; -; . OrthoDB EOG091G06HU; -; . PhylomeDB Q15172; -; . TreeFam TF105556; -; . Reactome R-HSA-195253; Degradation of beta-catenin by the destruction complex; . Reactome R-HSA-196299; Beta-catenin phosphorylation cascade; . Reactome R-HSA-2467813; Separation of Sister Chromatids; . Reactome R-HSA-2500257; Resolution of Sister Chromatid Cohesion; . Reactome R-HSA-389513; CTLA4 inhibitory signaling; . Reactome R-HSA-432142; Platelet sensitization by LDL; . Reactome R-HSA-4641262; Disassembly of the destruction complex and recruitment of AXIN to the membrane; . Reactome R-HSA-5339716; Misspliced GSK3beta mutants stabilize beta-catenin; . Reactome R-HSA-5358747; S33 mutants of beta-catenin aren't phosphorylated; . Reactome R-HSA-5358749; S37 mutants of beta-catenin aren't phosphorylated; . Reactome R-HSA-5358751; S45 mutants of beta-catenin aren't phosphorylated; . Reactome R-HSA-5358752; T41 mutants of beta-catenin aren't phosphorylated; . Reactome R-HSA-5467337; APC truncation mutants have impaired AXIN binding; . Reactome R-HSA-5467340; AXIN missense mutants destabilize the destruction complex; . Reactome R-HSA-5467348; Truncations of AMER1 destabilize the destruction complex; . Reactome R-HSA-5663220; RHO GTPases Activate Formins; . Reactome R-HSA-5673000; RAF activation; . Reactome R-HSA-5675221; Negative regulation of MAPK pathway; . Reactome R-HSA-6811558; PI5P; PP2A and IER3 Regulate PI3K/AKT Signaling; . Reactome R-HSA-68877; Mitotic Prometaphase; . SignaLink Q15172; -; . SIGNOR Q15172; -; . GeneWiki PPP2R5A; -; . GenomeRNAi 5525; -; . PRO PR:Q15172; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000066027; -; . CleanEx HS_PPP2R5A; -; . Genevisible Q15172; HS; . GO GO:0000775; C:chromosome; centromeric region; IEA:UniProtKB-SubCell GO GO:0005737; C:cytoplasm; IDA:BHF-UCL; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0031430; C:M band; ISS:BHF-UCL; . GO GO:0005634; C:nucleus; IEA:UniProtKB-SubCell; . GO GO:0000159; C:protein phosphatase type 2A complex; IDA:UniProtKB; . GO GO:0030018; C:Z disc; IDA:BHF-UCL; . GO GO:0019900; F:kinase binding; IPI:BHF-UCL; . GO GO:0019888; F:protein phosphatase regulator activity; TAS:ProtInc; . GO GO:0090005; P:negative regulation of establishment of protein localization to plasma membrane; IMP:BHF-UCL; . GO GO:0090219; P:negative regulation of lipid kinase activity; IMP:BHF-UCL; . GO GO:0035307; P:positive regulation of protein dephosphorylation; IMP:BHF-UCL; . GO GO:0007165; P:signal transduction; IEA:InterPro; . InterPro IPR016024; ARM-type_fold; . InterPro IPR002554; PP2A_B56; . PANTHER PTHR10257; PTHR10257; 1; . Pfam PF01603; B56; 1; . PIRSF PIRSF028043; PP2A_B56; 1; . SUPFAM SSF48371; SSF48371; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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